MOUNTAINS 2020

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MOUNTAIN
RESEARCH
CENTER

O Norte Somos Nós

CIMO is the winner of the "O Norte Somos Nós" Awards in
the category of Research. See video HERE

MOUNTAIN
RESEARCH
CENTER

See a short video
about us

MOUNTAIN
RESEARCH
CENTER

Polytechnic Institute
of Bragança

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FROM NATURE TO PRODUCTS, TOWARDS SUSTAINABILITY.

Sandrina Alves Heleno


Group: Sustainable Processes and Products
Supervisor: Isabel Cristina Fernandes Rodrigues Ferreira
Phone: 273303285
E-mail: sheleno@ipb.pt
ORCID: 000-0001-7224-1098
Scopus Author ID: 30067731800

Career

  • Since 2019: Junior Researcher (national funding by FCT, Foundation dor Science and Tecnhology) at CIMO-IPB, Portugal
  • 2015 - 2019: Pos-Doc researcher (SFRH/BPD/101413/2014)
  • 2015 - 2015: Pos-Doc researcher in the project ( NORTE-07-0124-FEDER- 0000014) - Polymer Reaction Engineering, Laboratory of Separation and Reaction Engineering

Qualifications

  • 2014 - PhD. in Sciences, specialty in chemistry, University of Minho Minho, Braga, Portugal
  • 2010 - MSc. in Biotechnology, Polytechnic Institute of Bragança, Portugal
  • 2008 - First degree in Biotechnological engineering, Polytechnic Institute of Bragança, Portugal

Awards and Honors

  • 2017 - Ward for the best oral communication in the VIII Fórum Ibérico de Úlceras e Feridas, Guimarães, Portugal

Interests

  • Extraction, purification and characterization of bioactive compounds such as mycosterols present in mushrooms
  • Bioactivity extracts and isolated compounds from mushrooms
  • Synthesis of mycosterol derivatives: chemical characterization, bioactivity and stability
  • Development of novel functional foods through the incorporation of extracts and bioactive compounds
  • Stabilization of extracts and isolated compounds in foodstuff
  • Development of cosmeceutical formulations through the incorporation of extracts and bioactive compounds
  • Stabilization studies of extracts and compounds in cosmeceutical formulations

Projects:

DeCodE - Bring natural colorants and preservers into a real alternative to artificial additives through a strategy of open data and experience based research
Funding body: PORTUGAL 2020 - SAICT
Reference:
Principal Investigator:Isabel Cristina Fernandes Rodrigues Ferreira
Start: 2017-04-01
End: 2019-10-01

Total results: 55
1
Gómez-Mejía E.,Roriz C.L.,Heleno S.A.,Calhelha R.,Dias M.I.,Pinela J.,Rosales-Conrado N.,León-González M.E.,Ferreira I.C.F.R.,Barros L.
Valorisation of black mulberry and grape seeds: Chemical characterization and bioactive potential
Food Chemistry, 337, , 2021

2
Roriz C.L.,Heleno S.A.,Carocho M.,Rodrigues P.,Pinela J.,Dias M.I.,Fernandes I.P.,Barreiro M.F.,Morales P.,Barros L.,Ferreira I.C.F.R.
Betacyanins from Gomphrena globosa L. flowers: Incorporation in cookies as natural colouring agents
Food Chemistry, 329, , 2020

3
Sampaio S.L.,Petropoulos S.A.,Alexopoulos A.,Heleno S.A.,Santos-Buelga C.,Barros L.,Ferreira I.C.F.R.
Potato peels as sources of functional compounds for the food industry: A review
Trends in Food Science and Technology, 103, 118-129, 2020

4
Carocho M.,Morales P.,Ciudad-Mulero M.,Fernández-Ruiz V.,Ferreira E.,Heleno S.,Rodrigues P.,Barros L.,Ferreira I.C.F.R.
Comparison of different bread types: Chemical and physical parameters
Food Chemistry, 310, , 2020

5
Fernandes F.A.,Carocho M.,Heleno S.A.,Rodrigues P.,Dias M.I.,Pinela J.,Prieto M.A.,Simal-Gandara J.,Barros L.,Ferreira I.C.F.R.
Effect of natural preservatives on the nutritional profile, chemical composition, bioactivity and stability of a nutraceutical preparation of aloe arborescens
Antioxidants, 9, , 2020

6
Martins N.,Heleno S.A.,Ferreira I.C.F.R.
An upcoming approach to alzheimer's disease: Ethnopharmacological potential of plant bioactive molecules
Current Medicinal Chemistry, 27, 4344-4371, 2020

7
Corrêa R.C.G.,Heleno S.A.,Alves M.J.,Ferreira I.C.F.R.
Bacterial resistance: antibiotics of last generation used in clinical practice and the arise of natural products as new therapeutic alternatives
Current Pharmaceutical Design, 26, 815-837, 2020

8
Rached W.,Barros L.,Ziani B.,Bennaceur M.,Calhelha R.,Heleno S.,Alves M.,Marouf A.,Ferreira I.
HPLC-DAD-ESI-MS/MS screening of phytochemical compounds and the bioactive properties of different plant parts of: Zizyphus lotus (L.) Desf.
Food and Function, 10, 5898-5909, 2019

9
Molina A.K.,Vega E.N.,Pereira C.,Dias M.I.,Heleno S.A.,Rodrigues P.,Fernandes I.P.,Barreiro M.F.,Kostić M.,Soković M.,Barreira J.C.M.,Barros L.,Ferreira I.C.F.R.
Promising antioxidant and antimicrobial food colourants from Lonicera caerulea L. var. Kamtschatica
Antioxidants, 8, , 2019

10
Taofiq O.,Heleno S.A.,Calhelha R.C.,Fernandes I.P.,Alves M.J.,Barros L.,González-Paramás A.M.,Ferreira I.C.F.R.,Barreiro M.F.
Phenolic acids, cinnamic acid, and ergosterol as cosmeceutical ingredients: Stabilization by microencapsulation to ensure sustained bioactivity
Microchemical Journal, 147, 469-477, 2019

11
Cardoso R.V.C.,Fernandes Â.,Heleno S.A.,Rodrigues P.,Gonzaléz-Paramás A.M.,Barros L.,Ferreira I.C.F.R.
Physicochemical characterization and microbiology of wheat and rye flours
Food Chemistry, 280, 123-129, 2019

12
Carocho M.,Heleno S.,Rodrigues P.,Barreiro M.F.,Barros L.,Ferreira I.C.F.R.
A novel natural coating for food preservation: Effectiveness on microbial growth and physicochemical parameters
LWT, 104, 76-83, 2019

13
Mandim F.,Barros L.,Heleno S.,Pires T.,Dias M.,Alves M.,Santos P.,Ferreira I.
Phenolic profile and effects of acetone fractions obtained from the inflorescences of: Calluna vulgaris (L.) Hull on vaginal pathogenic and non-pathogenic bacteria
Food and Function, 10, 2399-2407, 2019

14
Rudke A.R.,Heleno S.A.,Fernandes I.P.,Prieto M.A.,Gonçalves O.H.,Rodrigues A.E.,Ferreira I.C.F.R.,Barreiro M.F.
Microencapsulation of ergosterol and Agaricus bisporus L. extracts by complex coacervation using whey protein and chitosan: Optimization study using response surface methodology
LWT, 103, 228-237, 2019

15
Ziani B.E.C.,Heleno S.A.,Bachari K.,Dias M.I.,Alves M.J.,Barros L.,Ferreira I.C.F.R.
Phenolic compounds characterization by LC-DAD- ESI/MSn and bioactive properties of Thymus algeriensis Boiss. & Reut. and Ephedra alata Decne
Food Research International, 116, 312-319, 2019

16
Da Silva R.,Barreira J.,Heleno S.,Barros L.,Calhelha R.,Ferreira I.
Anthocyanin profile of elderberry juice: A natural-based bioactive colouring ingredient with potential food application
Molecules, 24, , 2019

17
Mandim F.,Barros L.,Calhelha R.,Abreu R.,Pinela J.,Alves M.,Heleno S.,Santos P.,Ferreira I.
Calluna vulgaris (L.) Hull: Chemical characterization, evaluation of its bioactive properties and effect on the vaginal microbiota
Food and Function, 10, 78-89, 2019

18
Taofiq O.,Heleno S.A.,Calhelha R.C.,Fernandes I.P.,Alves M.J.,Barros L.,González-Paramás A.M.,Ferreira I.C.F.R.,Barreiro M.F.
Mushroom-based cosmeceutical ingredients: Microencapsulation and in vitro release profile
Industrial Crops and Products, 124, 44-52, 2018

19
Almeida H.H.S.,Barros L.,Barreira J.C.M.,Calhelha R.C.,Heleno S.A.,Sayer C.,Miranda C.G.,Leimann F.V.,Barreiro M.F.,Ferreira I.C.F.R.
Bioactive evaluation and application of different formulations of the natural colorant curcumin (E100) in a hydrophilic matrix (yogurt)
Food Chemistry, 261, 224-232, 2018

20
Halla N.,Heleno S.A.,Costa P.,Fernandes I.P.,Calhelha R.C.,Boucherit K.,Rodrigues A.E.,Ferreira I.C.F.R.,Barreiro M.F.
Chemical profile and bioactive properties of the essential oil isolated from Ammodaucus leucotrichus fruits growing in Sahara and its evaluation as a cosmeceutical ingredient
Industrial Crops and Products, 119, 249-254, 2018

21
Francisco C.R.L.,Heleno S.A.,Fernandes I.P.M.,Barreira J.C.M.,Calhelha R.C.,Barros L.,Gonçalves O.H.,Ferreira I.C.F.R.,Barreiro M.F.
Functionalization of yogurts with Agaricus bisporus extracts encapsulated in spray-dried maltodextrin crosslinked with citric acid
Food Chemistry, 245, 845-853, 2018

22
23
Rached W.,Zeghada F.,Bennaceur M.,Barros L.,Calhelha R.,Heleno S.,Alves M.,Carvalho A.,Marouf A.,Ferreira I.
Phytochemical analysis and assessment of antioxidant, antimicrobial, anti-inflammatory and cytotoxic properties of Tetraclinis articulata (Vahl) Masters leaves
Industrial Crops and Products, 112, 460-466, 2018

24
Oludemi T.,Barros L.,Prieto M.A.,Heleno S.A.,Barreiro M.F.,Ferreira I.C.F.R.
Extraction of triterpenoids and phenolic compounds from: Ganoderma lucidum: Optimization study using the response surface methodology
Food and Function, 9, 209-226, 2018

25
Ziani B.E.C.,Barros L.,Boumehira A.Z.,Bachari K.,Heleno S.A.,Alves M.J.,Ferreira I.C.F.R.
Profiling polyphenol composition by HPLC-DAD-ESI/MSn and the antibacterial activity of infusion preparations obtained from four medicinal plants
Food and Function, 9, 149-159, 2018

26
Halla N.,Fernandes I.P.,Heleno S.A.,Costa P.,Boucherit-Otmani Z.,Boucherit K.,Rodrigues A.E.,Ferreira I.C.F.R.,Barreiro M.F.
Cosmetics preservation: A review on present strategies
Molecules, 23, , 2018

27
Taofiq O.,Heleno S.A.,Calhelha R.C.,Alves M.J.,Barros L.,González-Paramás A.M.,Barreiro M.F.,Ferreira I.C.F.R.
The potential of Ganoderma lucidum extracts as bioactive ingredients in topical formulations, beyond its nutritional benefits
Food and Chemical Toxicology, 108, 139-147, 2017

28
Rached W.,Bennaceur M.,Barros L.,Calhelha R.,Heleno S.,Alves M.,Carvalho A.,Marouf A.,Ferreira I.
Detailed phytochemical characterization and bioactive properties of: Myrtus nivelii Batt & Trab
Food and Function, 8, 3111-3119, 2017

29
Svobodova B.,Barros L.,Sopik T.,Calhelha R.,Heleno S.,Alves M.,Walcott S.,Kuban V.,Ferreira I.
Non-edible parts of Solanum stramoniifolium Jacq.-a new potent source of bioactive extracts rich in phenolic compounds for functional foods
Food and Function, 8, 2013-2021, 2017

30
Heleno S.A.,Rudke A.R.,Calhelha R.C.,Carocho M.,Barros L.,Gonçalves O.H.,Barreiro M.F.,Ferreira I.C.F.R.
Development of dairy beverages functionalized with pure ergosterol and mycosterol extracts: An alternative to phytosterol-based beverages
Food and Function, 8, 103-110, 2017

31
Svobodova B.,Barros L.,Calhelha R.,Heleno S.,Alves M.,Walcott S.,Bittova M.,Kuban V.,Ferreira I.
Bioactive properties and phenolic profile of Momordica charantia L. medicinal plant growing wild in Trinidad and Tobago
Industrial Crops and Products, 95, 365-373, 2017

32
Antonio A.L.,Pereira E.,Pinela J.,Heleno S.,Pereira C.,Ferreira I.C.F.R.
Determination of antioxidant compounds in foodstuff
Food Safety: Innovative Analytical Tools for Safety Assessment, 179-220, 2016

33
Heleno S.A.,Prieto M.A.,Barros L.,Rodrigues A.,Barreiro M.F.,Ferreira I.C.F.R.
Optimization of microwave-assisted extraction of ergosterol from Agaricus bisporus L. by-products using response surface methodology
Food and Bioproducts Processing, 100, 25-35, 2016

34
Taofiq O.,Heleno S.A.,Calhelha R.C.,Alves M.J.,Barros L.,Barreiro M.F.,González-Paramás A.M.,Ferreira I.C.F.R.
Development of Mushroom-Based cosmeceutical formulations with Anti-Inflammatory, Anti-Tyrosinase, antioxidant, and antibacterial properties
Molecules, 21, , 2016

35
Heleno S.A.,Diz P.,Prieto M.A.,Barros L.,Rodrigues A.,Barreiro M.F.,Ferreira I.C.F.R.
Optimization of ultrasound-assisted extraction to obtain mycosterols from Agaricus bisporus L. by response surface methodology and comparison with conventional Soxhlet extraction
Food Chemistry, 197, 1054-1063, 2016

36
Taofiq O.,Calhelha R.,Heleno S.,Barros L.,Martins A.,Santos-Buelga C.,Queiroz M.,Ferreira I.
The contribution of phenolic acids to the anti-inflammatory activity of mushrooms: Screening in phenolic extracts, individual parent molecules and synthesized glucuronated and methylated derivatives
Food Research International, 76, 821-827, 2015

37
Heleno S.,Ferreira R.,Antonio A.,Queiroz M.,Barros L.,Ferreira I.
Nutritional value, bioactive compounds and antioxidant properties of three edible mushrooms from Poland
Food Bioscience, 11, 48-55, 2015

38
Ferreira I.,Heleno S.,Reis F.,Stojkovic D.,Queiroz M.,Vasconcelos M.,Sokovic M.
Chemical features of Ganoderma polysaccharides with antioxidant, antitumor and antimicrobial activities
Phytochemistry, 114, 38-55, 2015

39
Heleno S.,Martins A.,Queiroz M.,Ferreira I.
Bioactivity of phenolic acids: Metabolites versus parent compounds: A review
Food Chemistry, 173, 501-513, 2015

40
Heleno S.,Barros L.,Martins A.,Queiroz M.,Morales P.,Fernández-Ruiz V.,Ferreira I.
Chemical composition, antioxidant activity and bioaccessibility studies in phenolic extracts of two Hericium wild edible species
LWT - Food Science and Technology, 63, 475-481, 2015

41
Heleno S.,Barros L.,Martins A.,Morales P.,Fernández-Ruiz V.,Glamoclija J.,Sokovic M.,Ferreira I.
Nutritional value, bioactive compounds, antimicrobial activity and bioaccessibility studies with wild edible mushrooms
LWT - Food Science and Technology, 63, 799-806, 2015

42
Heleno S.,Ferreira I.,Calhelha R.,Esteves A.,Martins A.,Queiroz M.
Cytotoxicity of Coprinopsis atramentaria extract, organic acids and their synthesized methylated and glucuronate derivatives
Food Research International, 55, 170-175, 2014

43
Heleno S.,Ferreira I.,Ćirić A.,Glamočlija J.,Martins A.,Queiroz M.,Soković M.
Coprinopsis atramentaria extract, its organic acids, and synthesized glucuronated and methylated derivatives as antibacterial and antifungal agents
Food and Function, 5, 2521-2528, 2014

44
Heleno S.,Ferreira I.,Esteves A.,Ćirić A.,Glamočlija J.,Martins A.,Soković M.,Queiroz M.
Antimicrobial and demelanizing activity of Ganoderma lucidum extract, p-hydroxybenzoic and cinnamic acids and their synthetic acetylated glucuronide methyl esters
Food and Chemical Toxicology, 58, 95-100, 2013

45
Heleno S.,Stojković D.,Barros L.,Glamočlija J.,Soković M.,Martins A.,Queiroz M.,Ferreira I.
A comparative study of chemical composition, antioxidant and antimicrobial properties of Morchella esculenta (L.) Pers. from Portugal and Serbia
Food Research International, 51, 236-243, 2013

46
Heleno S.,Barros L.,Martins A.,Queiroz M.,Santos-Buelga C.,Ferreira I.
Phenolic, polysaccharidic, and lipidic fractions of mushrooms from northeastern portugal: Chemical compounds with antioxidant properties
Journal of Agricultural and Food Chemistry, 60, 4634-4640, 2012

47
48
Reis F.,Heleno S.,Barros L.,Sousa M.,Martins A.,Santos-Buelga C.,Ferreira I.
Toward the Antioxidant and Chemical Characterization of Mycorrhizal Mushrooms from Northeast Portugal
Journal of Food Science, 76, , 2011

49
Heleno S.,Barros L.,Sousa M.,Martins A.,Santos-Buelga C.,Ferreira I.
Targeted metabolites analysis in wild Boletus species
LWT - Food Science and Technology, 44, 1343-1348, 2011

50
Grangeia C.,Heleno S.,Barros L.,Martins A.,Ferreira I.
Effects of trophism on nutritional and nutraceutical potential of wild edible mushrooms
Food Research International, 44, 1029-1035, 2011

51
Vaz J.,Heleno S.,Martins A.,Almeida G.,Vasconcelos M.,Ferreira I.
Wild mushrooms Clitocybe alexandri and Lepista inversa: In vitro antioxidant activity and growth inhibition of human tumour cell lines
Food and Chemical Toxicology, 48, 2881-2884, 2010

52
Heleno S.,Barros L.,Sousa M.,Martins A.,Ferreira I.
Tocopherols composition of Portuguese wild mushrooms with antioxidant capacity
Food Chemistry, 119, 1443-1450, 2010

53
Barros L.,Heleno S.,Carvalho A.,Ferreira I.
Lamiaceae often used in Portuguese folk medicine as a source of powerful antioxidants: Vitamins and phenolics
LWT - Food Science and Technology, 43, 544-550, 2010

54
55
Barros L.,Heleno S.,Carvalho A.,Ferreira I.
Systematic evaluation of the antioxidant potential of different parts of Foeniculum vulgare Mill. from Portugal
Food and Chemical Toxicology, 47, 2458-2464, 2009

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Phone: 273 303 382
Email: cimo@ipb.pt

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